Our research

C27 products are more than just cosmetics. They are true alchemical blends that naturally support skin regeneration and help maintain its vital balance (homeostasis), beauty, and ultimately, its longevity.

The skin is one of the most visible mirrors of the aging process—accelerated by our lifestyles, daily habits, stress levels, and environmental conditions. To care for our skin, we must stimulate the regeneration of skin proteins and protect it from excessive oxidative stress.

Aging is a natural and inevitable physiological process, but we have found a way to slow it down—by reducing the oxidation of the skin’s proteome.

Skin regeneration is the new anti-aging. It is the foundation of long-term skin health and longevity, starting from age 27. All our products are formulated with Centella Asiatica extract, the skin’s true longevity secret, in varying forms and concentrations.

CICA-MA2® is a patented, proprietary complex developed by C27. Clinically proven, this exclusive ingredient captures the purest and most active essence of the Centella Asiatica plant — combining Asiaticoside, Madecassoside, and Asiatic Acid in superior ratios and concentrations that do not occur naturally in the plant.

Various concentration levels were tested to determine the ideal formulation, ultimately revealing the powerful regenerative and reparative potential of the complex.

The CICA-MA2® complex underwent a series of in-depth studies on skin aging, conducted in collaboration with a specialized proteome research laboratory. These ex vivo tests demonstrated the complex’s extraordinary effects on two key fronts, slowing the oxidation of the skin proteome, the collection of all skin proteins, including collagen, keratins, and laminins, which serve as biomarkers of aging and regenerating these biomarkers, reversing signs of aging at the molecular level.

Among the biomarkers studied, two proteins in particular stood out for their strong response to CICA-MA2®:

Collagen XVII: A critical structural protein in the skin, Collagen XVII regulates the proliferation of epidermal cells by influencing the competition between skin stem cells. It is widely regarded as the skin’s longevity protein.
Keratin 14 :This essential protein plays a key role in epidermal renewal, helping to maintain an effective skin barrier, crucial for preserving skin longevity and resilience.

Centella Asiatica is an ancient medicinal plant, traditionally used in Ayurvedic medicine and other healing practices across South Asia. It is renowned for its powerful regenerative properties and is often referred to as the “plant of longevity.”

The Centella Asiatica used in C27 formulations is sourced exclusively from Madagascar, where it naturally contains a higher concentration of purified active compounds (heterosides).

It is cultivated manually, in harmony with local climate and seasonal cycles. This Centella-based economy directly supports local communities and contributes to their income, a form of eco-commerce aligned with our brand’s core values. A sustainable source, rooted in respect for people and the planet.

No-compromise formulas, expertly crafted by Michèle Evrard.

Each C27 formula is the result of advanced formulation expertise, continuously refined to replicate the skin’s natural structure and enhance product penetration. These are biomimetic formulations, meaning they blend seamlessly with the skin’s biological processes. This ensures optimal bioavailability of active ingredients and amplifies the formula’s effectiveness on the skin.

C27’s Green-Tech philosophy combines cutting-edge formulation technologies with high-performance clean ingredients, biotechnology, and green chemistry. Every formula reflects a no-compromise approach — in both active and non-active ingredients — to deliver the highest level of performance and integrity.